|
The following are Prophylactic Regimens
for the prevention of Bacterial
Endocarditis:
Dental, Oral, Respiratory
or Esophageal Procedures:
|
Allergy |
No to Penicillin |
Yes to Penicillin |
|
Able to take by mouth |
Yes |
Yes |
|
Agent |
Amoxicillin |
Clindamycin |
|
Regimen |
50 mg/kg/dose 1 hour before procedure |
20 mg/kg 1 hour before procedure |
|
Max Dose |
2.0 grams |
600 mg |
|
Allergy |
Yes to Penicillin |
Yes to Penicillin |
|
Able to take by mouth |
Yes |
Yes |
|
Agent |
Cephalexin or Cefadroxil |
Azithromycin or Clarithromycin |
|
Regimen |
50 mg/kg/dose 1 hour before procedure |
15 mg/kg 1 hour before procedure |
|
Max Dose |
2.0 grams |
500 mg |
|
Allergy |
Yes to Penicillin |
Yes to Penicillin |
|
Able to take by mouth |
No |
No |
|
Agent |
Clindamycin |
Cefazolin |
|
Regimen |
20 mg/kg IV 1/2 hour before procedure |
25 mg/kg IV 1/2 hour before procedure |
|
Max Dose |
600 mg |
1.0 gram |
Gastrointestinal and Genitourinary
Procedures:
|
Allergy |
No to Penicillin |
Yes to Penicillin |
|
Risk |
High |
High |
|
Agent |
Ampicillin plus Gentamicin |
Vancomycin Plus Gentamicin |
|
Regimen |
1/2 hr before procedure:
Ampicillin 50 mg/kg IV/IM & Gentamicin 1.5 mg/kg IM/IV
6 hr after procedure:
Ampicillin 25 mg/kg IM/IV OR Amoxicillin 25 mg/kg/ PO |
1/2 hr before procedure:
Vancomycin 20 mg/kg IV & Gentamicin 1.5 mg/kg IM/IV |
|
Max Dose |
Ampicillin 1gm
Amoxicillin 1gm |
Vancomycin 1.0 gm
Gentamicin 120 mg |
|
Allergy |
No to Penicillin |
No to Penicillin |
|
Risk |
Moderate |
Moderate |
|
Agent |
Ampicillin |
Amoxicillin |
|
Regimen |
50 mg/kg IM/IV 1/2 hr before procedure |
50 mg/kg PO
1 hr before procedure |
|
Max Dose |
2.0 gm |
2.0 gm |
|
Allergy |
Yes to Penicillin |
|
|
Risk |
Moderate |
|
|
Agent |
Vancomycin |
|
|
Regimen |
Vancomycin 20 mg/kg IV 1/2 Hr before
procedure |
|
|
Max Dose |
1.0 gm |
|
|
